Protease Inhibitors

MLN9708在水溶液或血浆中立即水解为具有具有生物活性的MLN2238。MLN2238抑制20S proteasome的胰凝乳蛋白酶等蛋白水解位点（β5），无细胞试验中IC50/Ki为3.4 nM/0.93 nM，对β1作用效果稍弱，对β2几乎没有抑制活性。.

MLN9708在水溶液或血浆中立即水解为具有具有生物活性的MLN2238。MLN2238抑制20S proteasome的胰凝乳蛋白酶等蛋白水解位点（β5），无细胞试验中IC50/Ki为3.4 nM/0.93 nM，对β1作用效果稍弱，对β2几乎没有抑制活性。.

MLN9708在水溶液或血浆中立即水解为具有具有生物活性的MLN2238。MLN2238抑制20S proteasome的胰凝乳蛋白酶等蛋白水解位点（β5），无细胞试验中IC50/Ki为3.4 nM/0.93 nM，对β1作用效果稍弱，对β2几乎没有抑制活性。.

MLN9708在水溶液或血浆中立即水解为具有具有生物活性的MLN2238。MLN2238抑制20S proteasome的胰凝乳蛋白酶等蛋白水解位点（β5），无细胞试验中IC50/Ki为3.4 nM/0.93 nM，对β1作用效果稍弱，对β2几乎没有抑制活性。.

MLN9708在水溶液或血浆中立即水解为具有具有生物活性的MLN2238。MLN2238抑制20S proteasome的胰凝乳蛋白酶等蛋白水解位点（β5），无细胞试验中IC50/Ki为3.4 nM/0.93 nM，对β1作用效果稍弱，对β2几乎没有抑制活性。.

Full-length recombinant, human MMP-13 fused to a His&#8226Tag sequence and expressed in S. frugiperda insect cells.

Biochem/physiol Actions Potent inhibitor of SUMO-specific protease 1 (SENP1) that increases SUMOylated proteins in PC3 cells Table of Contents Momordin &#921:c, a pentacyclic triterpenoid isolated from fruit of Kochia scoparia (L.) and other

Biochem/physiol Actions Potent inhibitor of SUMO-specific protease 1 (SENP1) that increases SUMOylated proteins in PC3 cells Table of Contents Momordin &#921:c, a pentacyclic triterpenoid isolated from fruit of Kochia scoparia (L.) and other

General description A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are

General description Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution: however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an

General description CLPP (caseinolytic mitochondrial matrix peptidase proteolytic subunit) protein contains an aqueous chamber formed by face-to-face assembly of the two heptameric rings that have proteolytic active sites within. It is a member of

General description The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity.