Transcription Factors

BAFF (B lymphocyte activating factor) is a member of the tumor necrosis factor (TNF) ligand family which is expressed in T Cells, macrophages, monocytes and dendritic cells. It is also known as BLyS, THANK, TALL, zTNF4 and TNFS20.

BAFF Receptor (BAFF-R), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFF-R is a type III transmembrane

Source: Recombinant GST-tagged protein expressed in E. coli Mr: 71.

Source: recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 41.

Source: Recombinant GST-tagged protein expressed in E. coli Mr: 73.

General description MYC&nbsp:oncogene is a global transcription factor. The gene is located on human chromosome 8q24.

InformationCBL0137 HCl CBL0137 (CBLC137, Curaxin 137) HCl activates p53 and inhibits NF-kB with EC50s of 0.37 μM and 0.47 μM in the cell-based p53 and NF-kB reporter assays, respectively. It also inhibits histone chaperone FACT (facilitates

Biochem/physiol Actions CBP or CREB-binding protein is a nuclear transcriptional coactivator protein that binds specifically to the PKA-phosphorylated form of the CREB protein. Microinjection of an anti-CBP antiserum into fibroblasts leads to

FUNCTION :Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors,

Chromeceptin is a cell-permeable benzochromene compound that blocks insulin-induced adipogenesis in 3T3-L1 cells (100% blockage at ≤ 20 ng/μl) and selectively suppresses IGF2- (insulin-like growth factor 2) dependent growth of HepG2 carcinoma cells

Application Complement factor D is a serine protease essential for the activation of the alternative pathway in the complement system. Research of complement factor D has revealed that a self inhibitory loop is responsible for switch from a resting

Extinction Coeff.A280 nm = 1.78 at 1.0 mg/mLMolecular weight53,000 Da (single chain)Purity&gt:90% by SDS-PAGEGeneral DescriptionComplement factor P (properdin) is purified from normal human serum. Factor P is a 53,000 dalton cationic protein that