Cell Receptors

Chemokine (C-X-C motif) receptor 1 (CXCR1) is a rhodopsin-like G protein-coupled receptor. It is one of two high-affinity receptors for the CXC chemokine interleukin-8 (IL-8), a major mediator of immune and inflammatory responses.

Opioid receptor family includes three classic receptors, µ, d, and ?, also known as OP1, OP2 and OP3, respectively. The receptors are G_i/o-coupled GPCRs which will reduce intracellular cAMP levels after activation.

Proteinase-activated receptors (PAR) are a subfamily of G-protein coupled, seven-transmembrane domain receptors, which are cleaved within the aminoterminal exodomain by certain serine proteinases at a specific peptide bond. Trypsin and mast cell

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific

Useful for studies involving adenylate cyclase, AMP, and related membrane-transport phenomena. Consists of a single A subunit surrounded by five polypeptide chains of the B subunits.

Cholera Toxin (CT) is secreted by Vibrio cholerae . CT upregulates cell surface molecules, such as co-stimulatory molecules and chemokine receptors in antigen presenting cells(APCs), murine and human dendritic cells (DCs).

The CHRNA5 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human CHRNA5. This antibody recognizes human, mouse,pig antigen.

Biochem/physiol Actions The complement system is a complex cascade involving proteolytic cleavage of serum glycoproteins often activated by cell receptors. This cascade ultimately results in induction of the inflammatory response, phagocyte

Antigen: CRTH2/DP2 protein amino acids 378-395 Host: rabbit Cross Reactivity: (+) human, mouse, and rat DP2 receptor Application(s): ICC and WB

Antigen: CRTH2/DP2 protein amino acids 2-21 Host: rabbit Cross Reactivity: (+) human, mouse, and rat DP2 receptor Application(s): ICC and WB

cAMP is a ubiquitous cellular second messenger that is a critical component of a signal transduction pathway linking membrane receptors and their ligands to the activation of internal cellular enzymatic activity and gene expression.