Topoisomerases

Biochem/physiol Actions Topoisomerase I inhibitor. Rubitecan induces protein- linked DNA single strand breaks, blocking DNA and RNA synthesis in dividing cells.

Rubitecan (RFS 2000), a Camptothecin derivative, is an orally active topoisomerase I inhibitor with broad antitumor activity, and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells.

Rubitecan (RFS 2000), a Camptothecin derivative, is an orally active topoisomerase I inhibitor with broad antitumor activity, and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells.

General description Human Sirtuin 7, GenBank Accession No. NM_016538), full length, MW = 46 kDa, expressed in E.

Labelled SN-38, a metabolite of Irinotecan, a DNA topoisomerase inhibitor.

Labelled SN-38, a metabolite of Irinotecan, a DNA topoisomerase inhibitor.

Labelled SN-38, a metabolite of Irinotecan, a DNA topoisomerase inhibitor.

Labelled SN-38, a metabolite of Irinotecan, a DNA topoisomerase inhibitor.

SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis.Form:Solid.

SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis.Form:Solid.

SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis.Form:Solid.

Telomerase-IN-3 is a telomerase inhibitor, which directly targets hTERT promoter activity. hTERT is the key component for maintenance of telomerase activity.Form:Solid.