Topoisomerases

Product description：Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).

Product description：Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).

Product description：Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).

Product description：Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).

Product description：Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).

Dxd-d 5 is a deuterium labeled Dxd. Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a) .IC50&amp: Target:Topoisomerase I 0.31 μM (IC 50 )In Vitro:Stable heavy isotopes

Antitumor and intercalating agent: inhibits DNA topoisomerase II.

Antitumor and intercalating agent: inhibits DNA topoisomerase II.

An inhibitor of topoisomerase II (IC₅₀ = 60.3 &muM) can have much greater potencies when evaluated in cell-based cytotoxicity assays (e.

Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC 50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.In VitroExatecan is a potent topoisomerase I inhibitor, with an IC 50 of 0.975 μg/mL. Exatecan Mesylate (DX-8951f)

Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC 50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.In VitroExatecan is a potent topoisomerase I inhibitor, with an IC 50 of 0.975 μg/mL. Exatecan Mesylate (DX-8951f)

Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC 50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.In VitroExatecan is a potent topoisomerase I inhibitor, with an IC 50 of 0.975 μg/mL. Exatecan Mesylate (DX-8951f)