Topoisomerases

Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC 50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.In VitroExatecan is a potent topoisomerase I inhibitor, with an IC 50 of 0.975 μg/mL. Exatecan Mesylate (DX-8951f)

Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC 50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.In VitroExatecan is a potent topoisomerase I inhibitor, with an IC 50 of 0.975 μg/mL. Exatecan Mesylate (DX-8951f)

Garenoxacin is an inhibitor of topoisomerase (Topo) II and acts as a des-F(6)-quinoline actibacterial agent.

Garenoxacin is an inhibitor of topoisomerase (Topo) II and acts as a des-F(6)-quinoline actibacterial agent.

Garenoxacin is an inhibitor of topoisomerase (Topo) II and acts as a des-F(6)-quinoline actibacterial agent.

Garenoxacin is an inhibitor of topoisomerase (Topo) II and acts as a des-F(6)-quinoline actibacterial agent.

Genz-644282 is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity(IC50=1.2 nM).

Genz-644282 is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity(IC50=1.2 nM).

Genz-644282 is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity(IC50=1.2 nM).

Genz-644282 is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity(IC50=1.2 nM).

Genz-644282 is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity(IC50=1.2 nM).

HIV-1 integrase inhibitor 8 is a HIV-1 integrase inhibitor, compound 8.In VitroHIV-1 integrase inhibitor 8 is against 3′-processing (TC) and strand-transfer (ST) activities in the presence of Mn 2+ as the cationic cofactor by gel assay with IC 50