Viral Proteins

A phytoxin that antagonizes chemokine receptor CCR5 binding (IC₅₀ = 40 &microM) to the envelop protein gp120 and to CD4, which is known to mediate HIV-1 viral entry into cells cytotoxic to CLL cells (LC50 = 8 nM).

PC786 is an inhaled respiratory syncytial virus ( RSV ) L protein polymerase inhibitor. PC786 demonstrates potent antiviral activity against RSV-A ( IC 50 &lt:0.09 to 0.71 nM) and RSV-B ( IC 50 , 1.3 to 50.6 nM).In VitroPC786 demonstrates a potent

Phosphonoacetic acid inhibits specifically human cytomegalovirus DNA synthesis in virus-infected human fibroblasts . It also inhibits the synthesis of herpes simplex virus DNA in infected cells and the activity of the virus-specific DNA polymerase

Phosphonoacetic acid inhibits specifically human cytomegalovirus DNA synthesis in virus-infected human fibroblasts . It also inhibits the synthesis of herpes simplex virus DNA in infected cells and the activity of the virus-specific DNA polymerase

Pimodivir (VX-787) is an orally bioavailable inhibitor of influenza A virus polymerases through interaction with the viral PB2 subunit.In VitroPimodivir rescues macrophages from virus-mediated death at non-cytotoxic concentrations 24 hpi. The EC 50

Pimodivir (VX-787) is an orally bioavailable inhibitor of influenza A virus polymerases through interaction with the viral PB2 subunit.In VitroPimodivir rescues macrophages from virus-mediated death at non-cytotoxic concentrations 24 hpi. The EC 50

Pimodivir (VX-787) is an orally bioavailable inhibitor of influenza A virus polymerases through interaction with the viral PB2 subunit.In VitroPimodivir rescues macrophages from virus-mediated death at non-cytotoxic concentrations 24 hpi. The EC 50

Pimodivir (VX-787) is an orally bioavailable inhibitor of influenza A virus polymerases through interaction with the viral PB2 subunit.In VitroPimodivir rescues macrophages from virus-mediated death at non-cytotoxic concentrations 24 hpi. The EC 50

Pocapavir (SCH-48973) is an orally active capsid inhibitor. Pocapavir prevents virion uncoating upon entry into the cell. Pocapavir has antiviral activity against polioviruses. Pocapavir also inhibits enterovirus infections.

Pocapavir (SCH-48973) is an orally active capsid inhibitor. Pocapavir prevents virion uncoating upon entry into the cell. Pocapavir has antiviral activity against polioviruses. Pocapavir also inhibits enterovirus infections.

Pocapavir (SCH-48973) is an orally active capsid inhibitor. Pocapavir prevents virion uncoating upon entry into the cell. Pocapavir has antiviral activity against polioviruses. Pocapavir also inhibits enterovirus infections.

Pocapavir (SCH-48973) is an orally active capsid inhibitor. Pocapavir prevents virion uncoating upon entry into the cell. Pocapavir has antiviral activity against polioviruses. Pocapavir also inhibits enterovirus infections.