Biochemicals

17(R)-HDoHE is the primary oxygenation product of docosahexaenoic acid (DHA) when exposed to aspirin-inhibited cyclooxygenase-2, where it serves as a precursor to resolvins. Resolvins are a group of polyhydroxylated metabolites of DHA found in the

17(R)-HDoHE is the primary oxygenation product of docosahexaenoic acid (DHA) when exposed to aspirin-inhibited cyclooxygenase-2, where it serves as a precursor to resolvins. Resolvins are a group of polyhydroxylated metabolites of DHA found in the

17(R)-Resolvin D1 exhibits a dose-dependent reduction in leukocyte infiltration in a murine model of peritonitis with maximal inhibition of ~35% at a 100 ng dose. In contrast to resolvin D1, the aspirin-triggered form resists rapid inactivation by

17(R)-Resolvin D1 exhibits a dose-dependent reduction in leukocyte infiltration in a murine model of peritonitis with maximal inhibition of ~35% at a 100 ng dose. In contrast to resolvin D1, the aspirin-triggered form resists rapid inactivation by

17-HETE is a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. This compount also inhibits proximal tubule ATPase activity by as much as 70% at a concentration of 2 μM.

17-HETE is a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. This compount also inhibits proximal tubule ATPase activity by as much as 70% at a concentration of 2 μM.

17(S)-HpDoHE is a mono-oxygenation product of docosahexaenoic acid in human leukocytes, human whole blood, human glial cells, and murine brain . 17(S)-HpDoHE is generally reduced to 17(S)-HDoHE, a compound that serves as a precursor to

17(S)-HpDoHE is a mono-oxygenation product of docosahexaenoic acid in human leukocytes, human whole blood, human glial cells, and murine brain . 17(S)-HpDoHE is generally reduced to 17(S)-HDoHE, a compound that serves as a precursor to

17,20:20,21-Bis(methylenedioxy)-5β-pregnan-3β-ol.

17,20:20,21-Bis(methylenedioxy)pregn-4-en-3-one.

ApplicationIntermediate in the preparation of Cortisol derivatives.

ApplicationIntermediate in the preparation of Cortisol derivatives.