Enzyme inhibitors and enzyme substrates

SB 216763SB-216763 was used to inhibit GSK-3β in human brain microvascular endothelial cell line6and colorectal cancer cells.7SB-216763 was used to inhibit GSK-3β in human brain microvascular endothelial cell line and colorectal cancer cells.

SB 216763SB-216763 was used to inhibit GSK-3β in human brain microvascular endothelial cell line6and colorectal cancer cells.7SB-216763 was used to inhibit GSK-3β in human brain microvascular endothelial cell line and colorectal cancer cells.

SB 216763SB-216763 was used to inhibit GSK-3β in human brain microvascular endothelial cell line6and colorectal cancer cells.7SB-216763 was used to inhibit GSK-3β in human brain microvascular endothelial cell line and colorectal cancer cells.

SB 216763SB-216763 was used to inhibit GSK-3β in human brain microvascular endothelial cell line6and colorectal cancer cells.7SB-216763 was used to inhibit GSK-3β in human brain microvascular endothelial cell line and colorectal cancer cells.

SB431542 is a potent and selective inhibitor of ALK5 with IC50 of 94 nM in a cell-free assay, 100-fold more selective for ALK5 than p38 MAPK and other kinases.A specific and selective inhibitor of TGF-β type I ALK receptors and Smad3.

SB431542 is a potent and selective inhibitor of ALK5 with IC50 of 94 nM in a cell-free assay, 100-fold more selective for ALK5 than p38 MAPK and other kinases.A specific and selective inhibitor of TGF-β type I ALK receptors and Smad3.

SB431542 is a potent and selective inhibitor of ALK5 with IC50 of 94 nM in a cell-free assay, 100-fold more selective for ALK5 than p38 MAPK and other kinases.A specific and selective inhibitor of TGF-β type I ALK receptors and Smad3.

SB525334 is a potent and selective inhibitor of TGFβ receptor I (ALK5) with IC50 of 14.3 nM, is 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6.A potent ATP-competitive inhibitor against receptor TbR-I/ALK5.

SB525334 is a potent and selective inhibitor of TGFβ receptor I (ALK5) with IC50 of 14.3 nM, is 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6.A potent ATP-competitive inhibitor against receptor TbR-I/ALK5.

SB525334 is a potent and selective inhibitor of TGFβ receptor I (ALK5) with IC50 of 14.3 nM, is 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6.A potent ATP-competitive inhibitor against receptor TbR-I/ALK5.

SB525334 is a potent and selective inhibitor of TGFβ receptor I (ALK5) with IC50 of 14.3 nM, is 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6.A potent ATP-competitive inhibitor against receptor TbR-I/ALK5.

Potent and selective TXA 2 antagonist.