Enzyme inhibitors and enzyme substrates

Sulindac (Clinoril) is a non-steroidal anti-inflammatory agent of the arylalkanoic acid class.Treatment of human colorectal cancer cell lines induces MRP1 and MRP3 but not other members of the MRP family. Reported to significantly increase the

Sulindac Sulfide is a potent γ-secretase modulator (GSM).Sulindac Sulfide selectively reduces Aβ42 production in favor of shorter Aβ species. Sulindac Sulfide can be used for researching Alzheimer’s disease.

Sulindac Sulfide is a potent γ-secretase modulator (GSM).Sulindac Sulfide selectively reduces Aβ42 production in favor of shorter Aβ species. Sulindac Sulfide can be used for researching Alzheimer’s disease.

Sulindac Sulfide is a potent γ-secretase modulator (GSM).Sulindac Sulfide selectively reduces Aβ42 production in favor of shorter Aβ species. Sulindac Sulfide can be used for researching Alzheimer’s disease.

Tacrolimus.

Tacrolimus.

Tacrolimus.

TCS 359, a 2-acylaminothiophene-3-carboxamide, is a potent and selective FLT3 inhibitor with an IC50 of 42 nM. TCS 359 inhibits MV4-11 cell proliferation with an IC50 of 340 nM.A cell-permeable thienylcarboxamide compound that acts as a potent,

TCS 359, a 2-acylaminothiophene-3-carboxamide, is a potent and selective FLT3 inhibitor with an IC50 of 42 nM. TCS 359 inhibits MV4-11 cell proliferation with an IC50 of 340 nM.A cell-permeable thienylcarboxamide compound that acts as a potent,

TCS 359, a 2-acylaminothiophene-3-carboxamide, is a potent and selective FLT3 inhibitor with an IC50 of 42 nM. TCS 359 inhibits MV4-11 cell proliferation with an IC50 of 340 nM.A cell-permeable thienylcarboxamide compound that acts as a potent,

TCS 359, a 2-acylaminothiophene-3-carboxamide, is a potent and selective FLT3 inhibitor with an IC50 of 42 nM. TCS 359 inhibits MV4-11 cell proliferation with an IC50 of 340 nM.A cell-permeable thienylcarboxamide compound that acts as a potent,

TDZD-8(NP 01139) is a selective inhibitor of GSK-3, a thiadiazolidinone derivative, non-ATP competitive inhibitor of GSK-3β (IC50 = 2 μM): does not inhibit Cdk-1/cyclin B, CK-II, PKA or PKC at &gt:100 μM.TDZD-8 has been used to study the role of