BIS-CYCLOHEXANONE OXALDIHYDRAZONE CRYSTALLINE (C15-1235-271)

Catalog No.: C15-1235-271
Mfr. No.: C9012-25G
Mfr. Name: Sigma-Aldrich
Qty/UOM: 25
UOM: GR

Price: $198.72

List Price: $220.80

Application Bis(cyclohexanone)oxaldihydrazone (Cuprizone) has been used in mice to study the effect of NG2 (neural/glial antigen 2) proteoglycan on toxic-induced demyelination. It has been used to induce demyelination in mice.

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Description
Specifications

Application

Bis(cyclohexanone)oxaldihydrazone (Cuprizone) has been used in mice to study the effect of NG2 (neural/glial antigen 2) proteoglycan on toxic-induced demyelination.
It has been used to induce demyelination in mice.
It has been used to study cuprizone-induced demyelination and remyelination in the corpus callosum of mice.

Biochem/physiol Actions

Bis(cyclohexanone)oxaldihydrazone (Cuprizone) is a copper chelator. It results in oligodendroglial cell death, thereby leading to demyelination, astrogliosis and microglia activation. Cuprizone is widely used to study mitochondrial dysfunction-associated primary demyelination and remyelination in the corpus callosum.

UPC:: 51144202
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: C9012-25G
CAS:: 370-81-0

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