Bis-PEG5-NHS ester is a PEG derivative containing two NHS ester groups. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.Features and Benefits· Reactive groups: NHS ester (both ends)· Reactive towards: amino groups (primary amines)· NHS esters react with—NH2 groups at pH 7-9, forming stable amide bonds· Water-soluble; compare to non-pegylated BS3 (also soluble) and DSS (water-insoluble)· Membrane-impermeable, allowing for cell surface labeling· Irreversibly crosslink proteins or peptides by flexible PEG spacer arms· Polyethylene glycol spacer arms help maintain conjugate solubility· Pure compound with defined structure and molecular weight, ensuring reproducible protein-modification effects· PEG spacer provides unique advantages, including increased stability, reduced tendency toward aggregation and reduced immunogenicity· Ideal for small molecule or peptide conjugations
Specifictaions: ≥98%
MDL Number: C22H32N2O13
Molecular Formula: 532.50
PubChem CID: 51340935
Isomeric SMILES: C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCC(=O)ON2C(=O)CCC2=O
- UPC:
- 51173208
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- B595340-250mg
- CAS:
- 756526-03-1
- Product Size:
- 250mg
