Bischloroanthrabenzoxocinone ((-)BABX) is a selective inhibitor of Type II fatty acid synthesis (FASII). BABX showed IC|50|values of 11.4 and 35.3 μg/ml in the S. aureus and E. coli FASII assays, respectively, with comparable antibacterial activities. Type II fatty acid synthesis (FASII) is essential to bacterial cell viability and is a promising target for the development of novel antibiotics. More recently, BABX has been shown to inhibit agonist binding LXR (Liver X receptors). The receptors regulate the expression of the ABCA1 gene, which mediates the efflux of cholesterol from cells. Specification: >99% Molecular Formula: C28H24Cl2O7 Molecular Weight: 543.39 PubChem CID: 57354898 Isomeric SMILES: C1=CC=C2C=C3C(=CC2=C1)C=CC4=C3C=CC5=C4OC=CC(=C(C5=O)Cl)Cl Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/B329372-SCI_5ddc173a54afb45abbdd514975efc958.pdf
- UPC:
- 12352101
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- B329372-500μg
- CAS:
- 866022-28-8
- Product Size:
- 500μg
- Precautionary Statement Codes:
- P264
