BM 567 is a dual acting antithrombogenic agent, acting as an inhibitor of TXA2 synthase and as an antagonist of the TXA2R (TP receptor), the G protein-coupled receptor mediating TXA2 activity in platelets and vascular smooth muscle. It also antagonizes the vascular smooth muscle TP receptor with an IC50 value of 1.1 nM. BM 567 is an inhibitor of platelet TX synthase with an IC50 value of 12 nM.Thromboxane A2 (TXA2) is a potent thrombogenic and vasoconstrictor eicosanoid, produced in large amounts by activated platelets. TXA2 has been found to be a causal factor in the onset of stroke and myocardial infarction. Specification: >98% Molecular Formula: C18H28N4O5S Molecular Weight: 412.5 PubChem CID: 9866368 Isomeric SMILES: CCCCCNC(=O)NS(=O)(=O)C1=C(C=CC(=C1)[N+](=O)[O-])NC2CCCCC2 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/B342537-SCI_bd517cb2c9660c6f3a39b277f273fbbd.pdf
- UPC:
- 51131700
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- B342537-1mg
- CAS:
- 284464-77-3
- Product Size:
- 1mg
- Precautionary Statement Codes:
- P264
