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BMS-986176 (C09-1113-195)

Aladdin

Catalog No.
C09-1113-195
Manufacturer No.
B648534-25mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA
Price: $1,904.88
List Price: $2,116.54

BMS-986176 (LX-9211) is a highly selective, brain-penetrant, potent AAK1 (adaptor associated kinase 1) inhibitor with an IC 50 of 2 nM. BMS-986176 can be used for neurodegenerative diseases researchIn VitroAdaptor associated kinase 1 (AAK1) is a

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BMS-986176 (LX-9211) is a highly selective, brain-penetrant, potent AAK1 (adaptor associated kinase 1) inhibitor with an IC 50 of 2 nM. BMS-986176 can be used for neurodegenerative diseases researchIn VitroAdaptor associated kinase 1 (AAK1) is a member of the Arkl/Prkl family of serine/threonine kinases. AAKl mRNA exists in two splice forms termed short and long. The long form predominates and is highly expressed in brain and heart. AAKl is enriched in synaptosomal preparations and is co-localized with endocytic structures in cultured cells. AAKl modulates clatherin coated endocytosis, a process that is important in synaptic vesicle recycling and receptor-mediated endocytosis. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IC50: 2 nM (AAK1). Specification: 0.98 Molecular Formula: C19H23F4N3O Molecular Weight: 385.4 PubChem CID: 118419773 Isomeric SMILES: CC(C)C[C@@](C)(COC1=C(N=C(C=C1)C2=CC(=NC=C2)C(F)F)C(F)F)N
UPC:
12352005
Condition:
New
Availability:
8-12 weeks
Weight:
1.06 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
B648534-25mg
CAS:
1815613-42-3
Product Size:
25mg


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