BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC 50 of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with K d s of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hyAppearance:SolidIC50& Target:IC50: 7.68 nM (PD-1/PD-L1 interaction)In Vitro:In a ELISA competition assay, BMSpep-57 inhibits PD-1/PD-L1 binding up to 98.1% 300 nM. And it shows a concentration dependent inhibition of PD-1/PD-L1 binding with an IC 50 of 7.68 nM. BMSpep-57 induced high levels of IL-2 at 1 µM and 500 nM concentBiological Activity:BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC 50 of 7.68u2009nM. BMSpep-57 hydrochloride binds to PD-L1 with K d s of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-5. Specifications and Purity: 99%. Molecular Formula: C89H127ClN24O19S. Molecular Weight: 1904.63.
- UPC:
- 12352107
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.09 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- B659281-1mg
- Product Size:
- 1mg
