The FMK peptides are potent, cell permeable, irreversible inhibitors. It is useful for in vitro and in vivo applications. BOC-ASP(OMe)-FMK is an inhibitor for general Caspases. The novel Boc-D(OMe)-FMK inhibitor synthesized using proprietary technology is cell permeable and irreversibly binds to activated caspases to block apoptosis. Apoptosis is a physiological form of cell death, which plays important role in embryogenesis, cellular homoestasis, tisue atrophy, and removal damaged and mutated cells. Caspases, which act as molecular chainsaw are the central components of apoptosis response. Caspases are cysteine proteases that cleave after aspartate residue in their substrates. At least 7 of 14 known mammalian caspases have important role in apoptosis.
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- UPC:
- 51321602
- Condition:
- New
- Availability:
- 3 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 03FK01103
- CAS:
- 634911-80-1
- Model Number:
- C814M82
- Temperature Control Device:
- Yes
