General description
Glypican-3 (GPC3) is a membrane-bound heparin sulfate proteoglycan known to participate in cell growth and differentiation. GPC3 expression has been observed in the majority of hepatocellular carcinomas (HCC), but is rarely expressed in non-neoplastic hepatic tissue, making it a useful marker for HCC. Aditionally, this marker is expressed in many yolk sac tumors.
Quality
![]() IVD | ![]() IVD | ![]() IVD | ![]() RUO |
Linkage
Glypican-3 Positive Control Slides, Product No. 261S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a trademark of Sigma-Aldrich Co. LLC
biological source: mouse. Quality Level: 100, 500. conjugate: unconjugated. antibody form: culture supernatant. antibody product type: primary antibodies. clone: 1G12, monoclonal. description: For In Vitro Diagnostic Use in Select Regions (See Chart). form: buffered aqueous solution. species reactivity: human. packaging: vial of 0.1 . mL concentrate (261M-94), vial of 0.5 . mL concentrate (261M-95), bottle of 1.0 . mL predilute (261M-97), vial of 1.0 . mL concentrate (261M-96), bottle of 7.0 . mL predilute (261M-98). manufacturer/tradename: Cell Marque™. . technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500. isotype: IgG1. control: hepatocellular carcinoma (HCC). shipped in: wet ice. storage temp.: 2-8°C. visualization: cytoplasmic. Gene Information: human ... GPC3(2719).- UPC:
- 51183103
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 261M-90