General description
A highly selective and competitive ETB receptor antagonist (IC50 = 1.2 nM).
Highly selective ETB-receptor antagonist (IC50 = 1.2 nM).
Biochem/physiol Actions
Cell permeable: no
Primary Target
ETB-receptor antagonist
Product does not compete with ATP.
Reversible: no
Target IC50: 1.2 nM as ETB-receptor antagonist
Warning
Toxicity: Standard Handling (A)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). DMSO and Methano:H₂O stock solutions are stable for up to 2 months at -20°C.
Other Notes
Okada, M., and Nishikibe, M. 2002. Cardiovasc. Drug Reviews20, 53.
Taniai, H., et al. 2001. Hepatology33, 894.
Fukuroda, T., et al. 1994. Biochem. Biophys. Res. Commun.199, 1461.
Ishikawa, K., et al. 1994. Proc. Natl. Acad. Sci. USA91, 4892.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51241518
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- 05-22-3838-5MG
