Brassinolide (C09-0752-043)

Brassinolide is a plant hormone; a natural steroid containing a seven-membered B-ring lactone, that promotes both cell elongation and cell devision and is used as a plant growth regulator.Description:IC50 Value: N/ABrassinolide is a plant sterol first isolated from pollen of rape (Brassica napus L.), Brassinolide could promote stem elongation and cell division.in vitro: Caspase-3 activity was obviously increased after brassinolide treatment. Western blot studies indicated that treatment with brassinolide triggered a time-dependent decrease in the expression of anti-apoptotic protein Bcl-2 [1].  After treatment of brassinolide under the concentration of 0.001 - 10.0 microg x mL(-1), the resistance of CCRF-VCR was reversed partly with the reversing folds respectively as 4.4 - 11.6 [2].  After brassinolide treatment, the expression of p53 in CCRF-VCR cells restored to the level of sensitive cells.in vivo: After oral administration of Brassinolide for consecutive 7 days(once every day),the levels of blood glucose were evaluated on the day 0 and the day 7 [3].Clinical trial: N/A A plant growth regulator. Specifications and Purity: ≥90.0%. MDL Number: MFCD00133310. Molecular Formula: C28H48O6. Molecular Weight: 480.69. PubChem CID: 115196. Isomeric SMILES: C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2COC(=O)[C@@H]4[C@@]3(C[C@H]([C@H](C4)O)O)C)C)[C@H]([C@@H]([C@@H](C)C(C)C)O)O. Related Document: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/B131571-SCI_19cbaab2c9e8570937c9f78ad45ac67c.pdf