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Brefeldin A (C15-1222-214)

Catalog No.
C15-1222-214
Manufacturer No.
B7651-5MG
Manufacturer Name
Sigma-Aldrich
Quantity
5
Unit of Measure
MG
Price: $372.86
List Price: $414.29

Chemical structure: macrolide Application Brefeldin A has been shown to increase CRISPR genome editing efficiency. To see other small molecule CRISPR enhancers, visit sigma.

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General description

Chemical structure: macrolide

Application

Brefeldin A has been shown to increase CRISPR genome editing efficiency. To see other small molecule CRISPR enhancers, visit sigma.com/CRISPR-enhancers.

Biochem/physiol Actions

Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus. BFA is an activator of the sphingomyelin cycle. Brefeldin A-mediated apoptosis has been observed in human tumor cells.

Brefeldin A has been shown to increase CRISPR-mediated homology-directed repair (HDR) efficiency.

UPC:
51281821
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
B7651-5MG


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