Broflanilide (C09-1112-990)

Broflanilide is a potential insecticide and metabolized to Desmethyl-Broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA Receptor , and inhibits S. litura RDL GABAR, with an IC 50 value of 1.3 nM.In VitroBroflanilide is an insecticide and metabolized to desmethyl-broflanilide, which is a potent and selective antagonist at the insect resistant-to-dieldrin (RDL) GABA receptor, and inhibits S. litura RDL GABAR, with an IC 50 value of 1.3 nM. Desmethyl-broflanilide shows weak activity against human GABA A α1β2γ2 receptor, the mammalian GABA A α1β3γ2 receptor and human glycine receptor (GlyR) α1β with IC 50 s of >3 μM, and less potently inhibits GlyR α1-A288Gβ and GlyR α1-A288G (IC 50 s, 0.706, 0.149 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid. Specification: 0.99 Molecular Formula: C25H14BrF11N2O2 Molecular Weight: 663.28 PubChem CID: 53341374 Isomeric SMILES: CN(C1=CC=CC(=C1F)C(=O)NC2=C(C=C(C=C2Br)C(C(F)(F)F)(C(F)(F)F)F)C(F)(F)F)C(=O)C3=CC=CC=C3