3-Bromopyruvic acid is a brominated derivative of pyruvic acid , which inhibits HXK II (hexokinase II) in cancer cells. As a result of this inhibition the cells are unable to metabolize glucose into ATP directly. Studies conducted on MCF-7 breast cancer cells show that 3-Bromopyruvic acid hydrate reduces the expression of Bcl-2, c-Myc and mutant p53, which are involved in the cell death signal transduction pathway. Alternate studies indicate that 3-Bromopyruvic acid hydrate is a very selective antibiotic, inhibiting the growth of certain yeasts.Affinity label for cysteine residues; Cross-linker between nucleic acids and proteins. Specification: 0.96 MDL Number: MFCD00002587 Molecular Formula: C3H3BrO3 Molecular Weight: 166.96 EC Number: 214-206-5 PubChem CID: 70684 Isomeric SMILES: C(C(=O)C(=O)O)Br Beilstein Registry Number: 1746786 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/B120321-SCI_dfbfde00af9e8298b54d5a6ec635f891.pdf
- UPC:
- 51283005
- Condition:
- New
- Availability:
- 2 weeks
- Weight:
- 6.74 Ounces
- HazmatClass:
- Yes
- WeightUOM:
- LB
- MPN:
- B120321-25g
- CAS:
- 1113-59-3
- Health Hazards:
- Corrosive
- Product Size:
- 25g
- Hazard Statement Codes:
- H314
- Precautionary Statement Codes:
- P280:P305+P351+P338
