BSTFA (with 1% TMCS)

Application

BSTFA (with 1% TMCS) may be used as a derivatizing agent in the following:

• Analysis of estrogenic compounds in water samples using gas chromatography coupled to mass spectrometry (GC-MS).
• Quantification of α-pyrrolidinovalerophenone (α-PVP) and its metabolites in urine samples using gas chromatography coupled to mass spectrometry (GC-MS).

Features and Benefits

• BSTFA is very versatile, reacting with a range of polar organic compounds and replacing active hydrogens with a −Si(CH₃)₃ (trimethylsilyl) group.
• Reacts rapidly and more completely than BSA.;
• TMCS increases the reactivity of BSTFA (or other silylation reagents).
• Amides and many secondary amines and hindered hydroxyls, incompletely derivatized by BSTFA alone, can be derivatized by adding 1-20% TMCS to BSTFA.
• Has good solvent properties and can function as a silylation reagent without additional solvents.
• Alternatively, the mixture is very soluble in most commonly used silylation solvents.

Legal Information

CERILLIANT is a registered trademark of Cerilliant Corporation