Butyrolactone 3, also called MB-3 is an inhibitor of Histone acetyltransferase GCN5 (general control of amino-acid synthesis 5). Gcn5 HAT activity is required to acetylate histone H3 lysine 9 (K9) and K14, which allows transcription elongation by relaxing nucleosomes. Butyrolactone 3 specifically inhibits Gcn5's HAT activity. It has been shown to display anti-inflammatory and anti-carcinogenic effects.
Specification: ≥95%
Molecular Formula: C9H12O4
Molecular Weight: 184.19
PubChem CID: 10081070
Isomeric SMILES: CCC[C@H]1[C@@H](C(=C)C(=O)O1)C(=O)O
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/B344763-SCI_2451ba2687f4485e03693a61a65b7fb9.pdf
- UPC:
- 51241918
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 0.07 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- B344763-25mg
- CAS:
- 778649-18-6
- Product Size:
- 25mg
- Hazard Statement Codes:
- H319
- Precautionary Statement Codes:
- P305+P351+P338:P280:P264
