Cabamiquine (DDD107498) succinate is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite , with an EC 50 of 1 nM against P. falciparum 3D7. Cabamiquine succinate inhibits protein synthesis by targeting eEF2/CaMKIII , with an EC 50 of 2 nM for WT- Pf eEF2In VivoCabamiquine (DDD107498) exhibits an ED 90 of 0.57 mg/kg after a single oral dose in mice infected with the rodent parasite P. berghei . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:CaMK III Plasmodium. Specification: 0.99 Molecular Formula: C31H37FN4O6 Molecular Weight: 580.65 PubChem CID: 138319698
- UPC:
- 51342400
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- C646406-50mg
- CAS:
- 2444781-71-7
- Product Size:
- 50mg
