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calmodulin, his.tag human, recombinant

CALMODULIN HISòTAG(R) HUMAN RECOMBINANT

Catalog No.
C005B-097901
Mfr. No.
208670-50UG
Mfr. Name
Sigma-Aldrich
Qty/UOM
50
UOM
UG
Price: $323.49
List Price: $359.43

Full-length, recombinant human calmodulin fused to a His • Tag sequence at the N-terminus. Contains four functional Ca 2+ -binding sites (aa 20-31 aa 56-67 aa 93-104 aa 129-140) with EF-hands (aa 7-42 aa 43-78 aa 80-115 aa 116-148) and

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General description

Full-length, recombinant human calmodulin fused to a His•Tag sequence at the N-terminus. Contains four functional Ca2+-binding sites (aa 20-31; aa 56-67; aa 93-104; aa 129-140) with EF-hands (aa 7-42; aa 43-78; aa 80-115; aa 116-148); and a ubiquitination site at Lys21. This preparation is qualified for use as a substrate for protein tyrosine kinases in in vitro assays. Through its interaction with Ca2+, calmodulin mediates the control of a large number of enzymes, including protein kinases and phosphatases. It is expected to be phosphorylated at Thr44 by CaMK4. In addition, it serves as a substrate for various protein tyrosine kinases.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In PBS, 0.2% Protease Inhibitor Cocktail Set VII (Cat. No. 539138).

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Other Notes

Chou, J.J., et al. 2001.Nat. Struct. Biol.8, 990.
Lennon, G., et al. 1996.Genomics33, 151.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Shipping Information:

Dry Ice Surcharge & Ice Pack Shipments: $40

More Information: https://cenmed.com/shipping-returns

UPC:
41116012
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
208670-50UG
Temperature Control Device:
Yes

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