Native Human Calpain-1 (u-Calpain) CAPN1, Human Erythrocyte direct from the manufacturer. Bulk qty. available.Calpain-1 (μ-Calpain) is a calcium activated neutral cysteine protease. It is a heterodimer of a Catalytic 80 kDa subunit and a 30 kDa subunit, which requires 50 μM Ca2+ for half-maximal activity in vitro. Its participation in events such as cell division, signal transduction, and long term potentiation has been suggested. Calpains have also been proposed to play a role in various pathological processes associated with altered metabolism and altered calcium homeostasis. One unit is defined as the amount of enzyme that will hydrolyze one ρmol Suc-LLVY-AMC per minute at 25°C using the Calpain Activity Assay Kit, Fluorogenic Ref: Vilei, E.E. et al. 1997. Journal of Biological Chemistry. 272. 41
Specification: ≥95%(SDS-PAGE)
- UPC:
- 51181624
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 0.07 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- np001116-100μg
- Product Size:
- 100μg
