Camptothecin-20(S)-O-propionate (CZ48), the C20-propionate ester of CPT, is a highly effective anticancer agent. Camptothecin-20(S)-O-propionate (CZ48) is a topoisomerase-Ι inhibitor .In VivoCamptothecin-20(S)-O-propionate (CZ48, gavage, 100 to 2000 mg/kg/day) exhibits anti-tumor activity in CLO-breast carcinoma (100 mg/kg) and PC3-prostate carcinoma (1000 mg/kg) models in mice. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: A tumor xenograft growing in a nude mouse (size, ∼1 cm 3 ). Dosage: 100-1000 mg/kg/day. Administration: Oral gavage, for 2, 4 and 6 days, respectively. Result: Exhibited anti-tumor effect.Form:Solid. Specification: 0.99 Molecular Formula: C23H20N2O5 Molecular Weight: 404.42 PubChem CID: 9887472 Isomeric SMILES: CCC(=O)O[C@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)CC
- UPC:
- 12352208
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- C646911-5mg
- CAS:
- 194414-69-2
- Product Size:
- 5mg
