General description

This Certified Spiking Solution^® is suitable for cannabidiolic acid testing methods by GC/MS, LC/MS or HPLC for applications in the testing of Cannabis potency or impurity profiling, pharmaceutical research, and forensic analysis. Cerilliant solution Certified Reference Materials (CRMs) of cannabinoids are supplied in a convenient, quantitative, US DEA-exempt solution format and with TK#s for Canadian customers.

Cannabidiolic acid (CBDA) is one of the main cannabinoids found in plants of the Cannabaceae family, such as hemp and cannabis. It occurs mostly in the leaves of the plant and on decarboxylation in the presence of light or heat forms cannabidiol (CBD). It is known to show anxiolytic, anti-inflammatory, anti-hyperalgesic, antiemetic, neuroprotective, and anticonvulsant activities.

Application

The Certified Reference Material (CRM) in solution can also be used as follows:

Determination of four cannabinoids from an oil matrix using reversed-phase high-performance liquid chromatography (RP-HPLC) combined with a diode array detector (DAD)
Analysis of hemp seed oil samples for identification and estimation of seven major cannabinoids by HPLC coupled to a UV detector
Separation and determination of CBD and CBDA from hemp oil samples using liquid-liquid extraction and HPLC-DAD
Multi-analysis of 11 cannabinoids in biomass and extracts of different cannabis varieties by an HPLC-UV method, following the International Conference on Harmonization (ICH) Tripartite Guideline for Validation of Analytical Procedures
Development and validation of an HPLC-DAD method for the simultaneous analysis of five major neutral and acidic cannabinoids in cannabis and hashish samples
Gas chromatography-mass spectrometry (GC-MS) analysis of ten main cannabinoids from hemp inflorescences following their silylation and esterification for derivatization

Features and Benefits

Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
Rigorously tested through real-time stability studies to ensure accuracy and shelf life
Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
Flame sealed under argon into ampoules for long-term shelf life
Offered in a convenient, DEA-exempt format to improve laboratory efficiency