General description
An active constituent of cayenne pepper with excitatory and desensitizing effects on a subset of primary afferent sensory neurons. An antagonist of acetylcholine-induced responses in rat PC12 cells. Exhibits anti-nociceptive and anti-inflammatory effects. Inhibits NF-κB activation by TNF. Reversibly inhibits platelet aggregation.
An active constituent of cayenne pepper. Has excitatory and desensitizing effects on a subset of primary afferent sensory neurons. An antagonist of acetylcholine-induced respones in rat pheochromocytoma cells. Exhibits antinociceptive and anti-inflammatory effects. Inhibits NF-κB activation by TNF. Reversibly inhibits platelet aggregation.
Warning
Toxicity: Toxic (F)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Other Notes
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Singh, S., et al. 1996. J. Immunol.157, 4412.
Nakazawa, K., et al. 1994. Br. J. Pharmacol.113, 296.
Simmons, D.D., et al. 1994. Int. J. Dev. Neurosci.12, 517.
Takaki, M., et al. 1994. J. Mol. Cell. Cardiol.26, 1227.
Bevan, S., and Szolcsanyi, J. 1990. Trends Pharmacol. Sci.11, 330.
Pernow, B., et al. 1985. J. Immunol.135, 8125.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51271605
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 211275-100MG