Carbonic Anhydrase from bovine erythrocytes (C09-0799-539)

Specificity:Blood CO2 transport and excretion is largely dependent on the rapid catalysis of the CO2 reactions within the erythrocyte by CA (Tufts et al. 2003). Bovine CA reversibly hydrates alkyl pyruvates and it exhibits hydratase activity toward a wide variety of substrates (Pocker et al. 1974, and Wells et al. 1975).Protein Accession Number: P00921CATH Classification (v. 3.2.0):Class: Alpha BetaArchitecture: RollTopology: Carbonic Anhydrase IIMolecular Weight:29.0 kDa (Theoretical)30 kDa (Lindskog et al. 1971)Optimal pH: 7.0-7.5 (Demir et al. 2000, and Tasgin et al. 2009)Isoelectric Point: 6.40 (Theoretical)Extinction Coefficient：50,070 cm-1M-1 (Theoretical)E1%, 280 = 19.0 (Nyman and Lindskog 1964)Active Site Residues：Histidine (H63)Asparagine (N66)Lysine (K126)Activators:HPO42- (Rowlett et al. 1991)SO32- (Rowlett et al. 1991)Inhibitors:Monovalent anions (Lindskog et al. 1971, and Ward and Cull 1972)Sulfonates and sulfonamides (Pocker and Watamori 1973, and Binford et al. 1974)Imidazole (Edsall 1968)Applications:CO2 determination in bloodElimination of CO2 in reagents for acidity testingCarboxy group transfersReduction reactions. Specification: ≥3,000 units/mg dry weight MDL Number: MFCD00081467 EC Number: 232-576-6 PubChem CID: 135330076 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/C128742-SCI_a1794de45c82f7d04fef0a403c1063de.pdf