Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone (C15-1235-273)

Sigma-Aldrich

Catalog No.: C15-1235-273
Manufacturer No.: C2920-10MG
Manufacturer Name: Sigma-Aldrich
Quantity: 10
Unit of Measure: MG

Price: $288.37

List Price: $320.41

Biochem/physiol Actions FCCP is a protonophore (H + ionophore) and uncoupler of oxidative phosphorylation in mitochondria. It is capable of depolarizing plasma and mitochondrial membranes.

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Description
Specifications

Biochem/physiol Actions

FCCP is a protonophore (H⁺ ionophore) and uncoupler of oxidative phosphorylation in mitochondria. It is capable of depolarizing plasma and mitochondrial membranes. FCCP has been shown to have a number of effects on cellular calcium. It also is reported to inhibit a background K⁺ current and induce a small inward current, reduce pH by 0.1 unit, and induce a rise of intracellular [Na⁺]. FCCP stimulates Mg²⁺-ATPase activity, inhibits β-amyloid production, and mimics the effect of selective glutamate agonist N-methyl-D-aspartate (NMDA) on mitochondrial superoxide production.

UPC:: 51332831
Condition:: New
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: C2920-10MG

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