Carboplatin (C09-0795-911)

Product DescriptionCarboplatin is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The development of carboplatin was inspired from the efficacy of its progenitor, Cisplatin (sc-200896), the first of this class of antineoplastic agents. The action of this group of platinum-based compounds is primarily attributed to DNA adduct formation, however, these molecules also bind other biological molecules, including enzymes, which might play a role in their mechanism of action.An antitumor agent that binds to DNA leading to apoptosisProduct ApplicationCarboplatin has been used: in chemotherapy-induced thrombocytopenia mouse model and treatment to induce cell death in a large subset of colorectal cancer cells in the evaluation of cell proliferation and chemosensitivity as a positive control for suppressed cell growthProduct classhAPIs, Metal based hAPIsChemical propertiesChemical formulaC6H12N2O4PtEmpirical formula[Pt(NH3)2(cbdc)]Molecular weight371.25MetalPtTheoretical metal content53Physical statepowderColorwhite. Specification: 0.98 MDL Number: MFCD00070464 Molecular Formula: C6H12N2O4Pt Molecular Weight: 371.25 EC Number: 255-446-0 PubChem CID: 426756 Isomeric SMILES: C1CC(C1)(C(=O)O)C(=O)O.[NH2-].[NH2-].[Pt+2] Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/C110682-SCI_ddc53a70b826883de6cc9575c2e56f69.pdf