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carmofur (c15-1253-018)

CARMOFUR (C005B-052804)

Catalog No.
C005B-052804
Mfr. No.
C1494-10MG
Mfr. Name
Sigma-Aldrich
Qty/UOM
10
UOM
MG
Price: $229.99
List Price: $255.54

Application Carmofur has been used as an inhibitor of acid ceramidase to study its effects on glucosylsphingosine (GlcSph) production in human embryonic kidney 293T (HEK293T) cells. It has also been used as an inhibitor of acid ceramidase to study

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Application

Carmofur has been used as an inhibitor of acid ceramidase to study its effects on glucosylsphingosine (GlcSph) production in human embryonic kidney 293T (HEK293T) cells. It has also been used as an inhibitor of acid ceramidase to study its effects on acid‐mediated hydrolysis of ceramide which kicks-in consumption and the generation of sphingosine .

Biochem/physiol Actions

Carmofur acts as an inhibitor of fatty acid amide hydrolase (FAAH), N-acylethanolamine acid amidase (NAAA) and acid ceramidase (ASAH1). Carmofur has a therapeutic activity against colorectal and cervical cancer. It can inhibit the severe acute respiratory syndrome (SARS)-CoV-2 main protease (Mpro) in vitro.

Carmofur is a derivative of fluorouracil, an antimetabolite used as an antineoplastic agent.

Shipping Information:

Hazmat Fee: $65.00 + applicable shipping charges are added after the order is placed.

More Information: https://cenmed.com/shipping-returns

UPC:
51171931
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
Yes
MPN:
C1494-10MG
CAS:
61422-45-5

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