ι-Carrageenan (C09-0797-763)

Carrageenans are mucopolysaccharides from the cell walls of the red algae. They are anionic linear polymers composed of 1,3α-1,4β-galactans having one (κ-), two (ι-) or three (λ-) sulfates per disaccharide unit. In ionic solutions, κ- and ι-carrageenans self-associate into helical structures that form rigid or flexible gels, respectively. λ-carrageenans do not form helices and are non-gelling. Carrageenans are used commercially as thickeners and stabilizing agents. Carrageenans are linear sulfated (IOTA, KAPA and GAMMA) glycans used as plant defense eliciting and anti-viral agents. Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. IOTA, KAPA and GAMMA carrageenans vary at the level of sulfation and may be studied comparatively to determine their differential protective, antiviral and immunosuppression activities. Specification: Refined stage MDL Number: MFCD00151512 EC Number: 232-949-3 PubChem CID: 11966245 Isomeric SMILES: C1[C@@H]2[C@@H]([C@H](O1)[C@H]([C@H](O2)O)OS(=O)(=O)[O-])O[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)OS(=O)(=O)[O-])O[C@@H]4[C@@H]([C@@H]5[C@H]([C@H](O4)CO5)O[C@H]6[C@@H]([C@H]([C@H]([C@H](O6)CO)OS(=O)(=O)[O-])O)O)OS(=O)(=O)[O-])O Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/C120988-SCI_bac3d4a00bd26ff83ecd9c8379d62031.pdf