CASIN (C15-1724-168)

Catalog No.: C15-1724-168
Mfr. No.: SML1253-5MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 5
UOM: MG

Price: $283.96

List Price: $315.51

Application CASIN has been used as a cell division control protein 42 homolog (Cdc42) inhibitor: to study its effects on the stimulation of extracellular vesicles (EVs) in intestinal epithelial cells to study its effects on mice jejunum to

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Description
Specifications

Application

CASIN has been used as a cell division control protein 42 homolog (Cdc42) inhibitor:

to study its effects on the stimulation of extracellular vesicles (EVs) in intestinal epithelial cells
to study its effects on mice jejunum
to study its effects on microbial adhesion-triggered endocytosis (MATE) vesicle morphology in segmented filamentous bacteria (SFB)-colonized mice

Biochem/physiol Actions

CASIN is an inhibitor of Cdc42 GTPase, a small GTPase of the Rho-subfamily that plays important roles in cytoskeleton organization, cell cycle progression, signal transduction, and vesicle trafficking. CASIN generated a rejuvenated phenotype of Hematopoietic stem cells (HSCs), reversing the aging-related and polarity phenotype of aged HSCs to that of young HSCs in vivo..

UPC:: 41116127
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML1253-5MG
CAS:: 425399-05-9

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