General description
A potent and irreversible inhibitor of caspase-9 (ICE-LAP6, Mch6). Reported to reduce myocardial infarct size during reperfusion (~70 nM).
A potent, irreversible inhibitor of caspase-9. Reported to reduce myocardial infarct size during reperfusion (~70 nM).
Biochem/physiol Actions
Cell permeable: yes
Primary Target
caspase-9
Product does not compete with ATP.
Reversible: no
Target IC50: 70 nM against caspase-9
Warning
Toxicity: Standard Handling (A)
Sequence
Ac-Leu-Glu-His-Asp-CMK
Other Notes
Mocanu, M.M., et al. 2000. Br. J. Pharmacol.130, 197.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51321815
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- 218728-1MG
- CAS:
- 403848-57-7
