Cathepsin B, a cysteine proteinase, is located in lysosomes and is involved in tissue degradation and restructuring. Specifically, cathepsin B is believed to be involved in the intracellular digestion of extracellular proteins taken up by endocytosis. Ref: Rich D.H., Brown M.A. and Barrett A.J. 1986 Biochem J, 235, 731-734. Product Citations:Armstrong, Andrea, Niklas Mattsson, Hanna Appelqvist, Camilla Janefjord, Linnea Sandin, Lotta Agholme, Bob Olsson et al. "Lysosomal Network Proteins as Potential Novel CSF Biomarkers for Alzheimer’s Disease."Neuromolecular medicine 16, no. 1 (2014): 150-160.Watson, Andre, Cara Yocum, Vaibhav Pandit, and Shiva P. Kotha. "Optimizing Polymeric Nanoparticle Core Designs for Gene Delivery." In Bioengineering Conference (NEBEC), 2013 39th Annual Northeast, pp. 1-2. IEEE, 2013.Toneff, Thomas, Lydiane Funkelstein, Charles Mosier, Armen Abagyan, Michael Ziegler, and Vivian Hook. "Beta-Amyloid Peptides Undergo Regulated Co-Secretion with Neuropeptide and Catecholamine Neurotransmitters."Peptides (2013).Elie, Benelita Tina, Vasilena Gocheva, Tanaya Shree, Stacie A. Dalrymple, Leslie J. Holsinger, and Johanna A. Joyce. "Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model." Biochimie 92, no. 11 (2010): 1618-1624.
Specification: ≥95%(SDS-PAGE), Extinction Coefficient: 2.0
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/NP001112-SCI_2a437408d16cce81ec790de189cf3f92.pdf
- UPC:
- 12352204
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 0.07 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- np001112-25μg
- Product Size:
- 25μg
