CAY10622 is a potent, ureidobenzamide inhibitor of ROCK-I and ROCK-II kinases with IC50 values of 6 and 4 nM, respectively. It is inactive against an additional 44 kinases. ROCK-I and ROCK-II act downstream of the G protein Rho to regulate cytoskeletal stability. The Rho kinases play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewa. Molecular Formula: C25H25N5O3 Molecular Weight: 443.5 PubChem CID: 44819541 Isomeric SMILES: C1CNCC2=C1C=CC(=C2)NC(=O)C3=CC=CC(=C3)CNC(=O)NC4=CC=C(C=C4)C(=O)N Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/C342140-SCI_f260c4b4b6a55fa3a6468cccbe3c36bc.pdf
- UPC:
- 12352005
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- C342140-1mg
- CAS:
- 1038549-25-5
- Product Size:
- 1mg
- Precautionary Statement Codes:
- P264
