Mouse anti Human/Monkey CD154/CD40L Antibody, Monoclonal (5C8), could be used for in vitro blocking of CD40/CD40L signaling, in vivo blocking of CD40/CD40L signaling, IP, Flow and so on.Application:in vitro blocking of CD40/CD40L signaling: Use at an assay dependent concentration.in vivo blocking of CD40/CD40L signaling: Use at an assay dependent concentration.IP: Use at an assay dependent concentration.Flow: Use at an assay dependent concentration.Protein FunctionMediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching.Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
Specification: Validated, Azide Free, Carrier Free, ≥95%(SDS-PAGE), Lot by Lot
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/AB132316-SCI_251cc6f627143df76c2103b656edc1f0.pdf
- UPC:
- 41116128
- Condition:
- New
- Availability:
- 5-10 days
- Weight:
- 0.07 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- Ab132316-100μg
- Product Size:
- 100μg
