Cell Biology

Three distinct signaling pathways lead to apoptosis. The death receptor and mitochondrion pathways are the two mains, which involve respectively caspase-8 and caspase-9.

Three distinct signaling pathways lead to apoptosis. The death receptor and mitochondrion are the two main pathways which involve caspase-8 and caspase-9, respectively.

Caspase-3 (EC 3.4.

Caspase 3 is a cytosolic protein present as a 32 kDa proenzyme in cells. It is activated by proteolytic cleavage into the 20 kDa (p20) and 11 kDa (p11) active subunits when cells undergo apoptosis.

Caspase-3 (CPP32, Apopain) is the most extensively studied apoptotic protein. Caspase-3 is synthesized as an inactive proenzyme (32 kDa) that is processed in cells undergoing apoptosis by self-proteolysis and/or cleavage by another upstream

Caspase-3 (CASP3) belongs to the class of cysteine proteases. CASP3&nbspis an executioner caspase, which is cleaved and activated with the help of caspase-8 and caspase-9 initiator caspases.

Caspase-3 (CASP3) belongs to the class of cysteine proteases. CASP3&nbspis an executioner caspase, which is cleaved and activated with the help of caspase-8 and caspase-9 initiator caspases.

Caspase-3 (CASP3) belongs to the class of cysteine proteases. CASP3&nbspis an executioner caspase, which is cleaved and activated with the help of caspase-8 and caspase-9 initiator caspases.

Anti-Caspase 8 antibody, Mouse monoclonal (mouse IgM isotype) is derived from the CAS8 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with a recombinant human caspase 8. Caspase 8 gene is

Anti-Caspase 9 is developed in rabbit using a synthetic peptide corresponding to amino acid of human procaspase 9 with N-terminal added lysine conjugated to keyhole limpet hemocyanin (KLH) with glutaraldehyde. Caspase 9/CASP9 (Mch6, ICE-LAP6,

Specificity Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases.

Monoclonal Anti-Caspase 9 (mouse IgG1 isotype) is derived from the CAS9 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with a synthetic peptide corresponding to amino acids of human caspase 9