Cell Biology

The gene IGF2BP1 (insulin-like growth factor 2 mRNA-binding protein 1) is mapped to human chromosome 17q21. It belongs to the IGF (insulin-like growth factor)-II mRNA-binding proteins family.

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IGF2BP3 is an mRNA binding protein that regulates cell adhesion and invasion. This protein has been associated with carcinogenesis and may be used as a marker for cervical cancer .

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IGF2R (insulin-like growth factor 2 receptor) is a transmembrane glycoprotein. It is one of the two mannose 6-phosphate (M6P) receptors found in mammalian cells.

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