Interleukins

The Corning portfolio of cytokines, growth factors, and media supplementation offers a wide array of proteins that result in proliferation or differentiation of the affected cells. Vialed, highly purified growth factors with high biological activity

IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune

Application Interleukin-10 (IL-10) from rat has been used to study the anti-allodynic effect of IL-10 in rat model. Biochem/physiol Actions Interleukin-10 is an important regulator of the functions of lymphoid and myeloid cells.

Application Interleukin-10 (IL-10) from rat has been used to study the anti-allodynic effect of IL-10 in rat model. Biochem/physiol Actions Interleukin-10 is an important regulator of the functions of lymphoid and myeloid cells.

Recombinant, human interleukin-10 expressed in S. frugiperda insect cells.

Application Interleukin-12 (IL-12) from mouse has been used to study the effect of IL-12 on Th1 (type 1 T helper) immunity in Mongolian gerbils ( Meriones unguiculatus ) infected with Sporothrix schenckii . It has been used as a standard in ELISA

Application Interleukin-12 (IL-12) human has been used to study IL-12 mediated enhancement of IL-12R&#9462 (IL-12 receptor) expression. Biochem/physiol Actions Interleukin-12 (IL-12) was identified as a factor secreted by human Epstein-Barr

Biochem/physiol Actions Interleukin-12 (IL-12) was identified as a factor secreted by human Epstein-Barr (EBV)-transformed B cell lines. IL-12, or Natural Killer Cell Stimulatory Factor (NKSF), is a 75 kDa disulfide-linked heterodimer of a 35 kDa

Interleukin-12 (IL-12) is a potent regulator of cell mediated immune responses and it induces IFN-gamma production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes, and connective tissue type mast cells.

Recombinant, human interleukin-12 expressed in S. frugiperda insect cells.

Biochem/physiol Actions Interleukin-13 is a pleiotropic cytokine produced by activated Th2 cells in the mouse and human. IL-13 is secreted mainly as an unglycosylated protein of 132 amino acids with a molecular weight of 10,000 daltons.

Biochem/physiol Actions IL-13 is known to be overexpressed in glioblastoma tumors and cell lines. Elevated IL-13 expression is also observed in parasitic infections.