Interleukins

Specificity The antibody will neutralize the biological activity of recombinant human IL-1&#946. It will not neutralize the activity of recombinant human IL-&#945, recombinant mouse IL-1&#945, or recombinant mouse IL-1&#946.

Interleukin-6 is a pleotropic cytokine involved in hematopoiesis, inflammation and immune response. IL-6 is secreted by macrophages, dendritic cells and B cells, in response to TNF-&#945, PGDF and IL-1.

Interleukin-8 or CXCL8 (IL-8) is a proinflammatory chemokine that belongs to the C-X-C family. Monocytes and macrophages are the primary sources of IL-8 but it is also secreted by most nucleated cells.

Cell Line Origin Mouse NS1 x Mouse BALB/c spleen Cell Line Description The antibody is directed against Interleukin 4 (IL-4) but does not inhibit the biological activity of the cytokine. OX-87 is non-competitive with OX-81 (Sigma Catalogue number.

Cell Line Origin Mouse P3X63Ag8 x Rat OFA spleen Cell Line Description The antibody is directed against the murine T cell IL-2 receptor. It inhibits IL-2 driven cell proliferation of T cells and B cells.

PrEST Antigen ILF2 interleukin enhancer binding factor 2, 10

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