Protein L Products

Specificity This antibody reacts to Histone H3 trimethylated at Lysine 4 (K4me3). No cross reactivity with monomethylated Lysine 4 (K4me1) or dimethylated Lysine 4 (K4me3), or other methylation in histone H3.

Specificity This antibody reacts to Histone H3 trimethylated at Lysine 79 (K79me3). No cross reactivity with monomethylated Lysine 79 (K79me1) or dimethylated Lysine 79 (K79me2), or other methylations in histone H3.

General description Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes

General description Histone H3 is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.

Tyrosine hydroxylase plays an important role in the physiology of adrenergic neurons. It is the first and rate-limiting enzyme involved in the biosynthesis of the catecholamines Dopamine and Norepinephrine from tyrosine.

The gene VANGL1 (vang-like protein 1) is mapped to human chromosome 1p13. The encoded protein is a transmembrane protein and a component of the Wnt-PCP (planar cell polarity) pathway.

Immunogen VANGL1 (NP_620409.1, 1 a.

General description Anti-VANGL1 Antibody detects endogenous levels of total VANGL1 protein. The gene VANGL1 (vang-like protein 1) is mapped to human chromosome 1p13.

ATP-dependent zinc metalloprotease YME1L1 is an enzyme encoded by YME1L1 gene. It belongs to the family of ATPases associated with a variety of cell activities (AAA family).

Consanguineous: No Homozygous: No Cell Line Description This cell line is an Epstein-Barr Virus (EBV) transformed lymphoblastoid line and is part of the Human Leukocyte Antigen (HLA) Typed Collection maintained by the European Collection of Cell

Cell Line Origin Human Caucasian acute lymphoblastic leukaemia Cell Line Description A T lymphoblastoid line obtained from the peripheral blood of an 11 year old Caucasian male with acute lymphoblastoid leukaemia which has been passaged eight times

General description CD152 (CTLA-4 (cytotoxic T-lymphocyte associated protein 4)) and CD28 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. Both CD152 and CD28 are composed of a single Ig V-like