General description
CellASIC® ONIX switching plate mammalian cells (4 chambers) enable continuous perfusion culture for live cell analysis. Laminar flow provides a rapid and uniform solution exchange for maximum cell health. The glass cover slide bottom surface ensures the highest resolution of optical viewing.
Application
CellASIC® ONIX switching plate mammalian cells(4 chambers) have been used:
- in live-cell imaging to study the contribution of phi-particle in the autoinhibition of dynein and the activation of dynein by dynactin
- in live-cell imaging of fcSAgA binding and immunoglobulin M surface clustering by fluorescence microscopy
- in multiple epidermal growth factor (EGF)pulse experiments
- time-lapse analysis of adherent cells
- long-term continuous perfusion experiments (3 days typical)
- solution exchange experiments (induction, inhibition, drug dosing, etc.)
- automated immunostaining and on-demand fixation of live cells within the culture chamber
- comparison of up to four different cell types or exposure conditions (media components) in parallel, temperature, and gas atmospheric control (temperature shift, anoxic conditions, etc.)
Features and Benefits
- Compatible with CellASIC® ONIX2 Microfluidic system and ONIX2 Manifolds
- Enables perfusion-based, long-term, live-cell analysis with solution switching
- The plate offers a controlled and dynamic microenvironment for 2D and 3D cell cultures
Legal Information
CELLASIC is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 41116113
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- M04S-03-5PK
