Centricon® Plus Centrifugal Filter

Filter Type: Ultrafiltration The Centricon Plus-70 centrifugal filter is a disposable, single-use device designed for rapid processing of aqueous biological solutions in volumes ranging from 15 to 70 mL. It is compatible with swinging-bucket centrifuges only. The Centricon Plus-70 device can concentrate most 70 mL solutions down to 350 μL in just 25 minutes (some solutions may take slightly longer). •90% typical recovery •50X to 200X concentration •Low hold-up volume •Polypropylene housing minimizes binding •Deadstop prevents spinning to dryness •Ready to use. Nothing to assemble Applications: •Concentrating and desalting chromatography column eluates •Concentrating monoclonal antibodies •Concentrating proteins or viruses from culture supernatants •Clarifying tissue homogenates and cell lysates •Buffer exchange or diafiltration Application 3 kDa cutoff, 15 mL to 70 mL volume

Q1: What sample volume can the Centricon Plus-70 filter process? A: The Centricon Plus-70 centrifugal filter is designed for processing aqueous biological solutions in volumes ranging from 15 mL to 70 mL.   Q2: What is the typical concentration factor achieved with the Centricon Plus-70? A: The Centricon Plus-70 can achieve typical concentration factors ranging from 50X to 200X, depending on the solution.   Q3: What are some typical applications for the Centricon Plus centrifugal filter? A: Common applications include concentrating antibodies and proteins, desalting chromatography eluates, clarifying cell lysates, and performing buffer exchange or diafiltration.