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CFTR Cl- channel activator found in aloe. It increases colonic fluid secretion, decreases angiogenesis, and induces apoptosis in glioma cells. (C08-0489-082)

Thomas Scientific

Catalog No.
C08-0489-082
Manufacturer No.
A4617-100 mg
Manufacturer Name
LKT Laboratories, Inc
Quantity
1
Unit of Measure
EA
Price: $322.40
List Price: $358.23

Aloe emodin is an anthraquinone found in the aloe plant. Aloe emodin is most commonly known for its stimulant-laxative action, but also shows antioxidative, anticancer chemotherapeutic, and anti-angiogenic activity.

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Aloe emodin is an anthraquinone found in the aloe plant. Aloe emodin is most commonly known for its stimulant-laxative action, but also shows antioxidative, anticancer chemotherapeutic, and anti-angiogenic activity. This compound activates CFTR Cl- channels in the colon, potentially increasing fluid secretion and resulting in laxative activity. Aloe emodin acts on a number of targets in cellular models of cancer, including p65lck, ERa, NF-?B, and mTORC2. Additionally, aloe emodin induces apoptosis in glioma models through disruption of the mitochondria membrane potential.
UPC:
41122409
Condition:
New
Availability:
3 Days
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
A4617-100 mg
CAS:
481-72-1


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