General description
CHAPS is a non-denaturing, zwitterionic sulfobetaine detergent. It is mild and solubilizes membrane proteins and receptors. It is useful for breaking protein-protein interactions. It is a derivative of the naturally occurring bile salts. It has small micellar molecular weight (6,150) and high critical micellar concentration (6 - 10 mM) allowing it to be removed from samples by dialysis.
Application
CHAPS has been used:
- For membrane permeabilization of cells
- As a component in lysis buffer for homogenization of liver tissues as well as adipose tissue
- As a component in denaturing buffer in enzyme characterization
- As a component of 2D- sample buffer in 2D electrophoresis
- For protein solubilization in isoelectric focusing
- UPC:
- 51413107
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- C9426-5G